Stem Cell Research / Regenerative Medicine

Video: A Story of Recovering from Cancer using an Adult Stem Cell Transplant

Today the Charlotte Lozier Institute releases its fourth Stem Cell Research Facts video; this story features Cindy Schroeder’s recovery from multiple myeloma after an adult stem cell transplant. Cindy Schroeder had always lived an active life. A wife, mother of three, and special education teacher, Cindy drove more than 150 miles each day from school to school before returning home. Her life changed, however, when she began experiencing a crippling exhaustion upon waking, coughs that never seemed to go away, and eventually even trouble breathing. “Everything simple for others became a major deal for me,” recalled Cindy. Finally, after a bout of coughing up blood one day, Cindy’s husband urged her to visit the doctor. The diagnosis was multiple myeloma, a blood cancer in which abnormal blood cells accumulate in the bone marrow, interfering with the production of normal blood cells. Multiple myeloma is considered incurable, but treatable. “We were in the room and the doctor told her, ‘Cindy, you have cancer,’” says Ralph Ostmeyer, Cindy’s father. “She started to cry, and he says, ‘Cindy, don’t cry, we have a cure. It’s (adult) stem cell. You are a good candidate and the success rate is excellent if we can get good cells from your body.’ So that’s what we set out to do.” Watch Cindy share her road to recovery surrounded by loving family in CLI’s new video — https://lozierinstitute.org/video-brink-back-story-recovering-cancer-using-adult-stem-cell-transplant/ Many others like Cindy are currently being treated using ethically-derived, non-controversial adult stem cell transplants, which do not require the destruction of young human life. In fact, well over one million patients worldwide have been treated using adult stem...

U.S. House: Passed Ban on Production of 3-Parent Human Embryos & Reauthorized Programs Using Ethical Adult Stem Cells

US: Legislation Passes to Ban Production of 3 Parent Embryos The US House of Representatives passed legislation banning the creation of 3 parent embryos. This past year, Chinese, British and American scientists have been praising the potential of genetically modified human embryos, a practice the UK parliament approved earlier this year. In the US, while federal funding for research that creates or destroys a human embryo is prohibited, there is no prohibition on the practice in a clinical setting. The new legislation, sponsored by pro-life advocate Rep Robert Aderholt, remedies that by prohibiting “research in which a human embryo is intentionally created or modified to include a heritable genetic modification”. The Aderholt language was included in the Omnibus spending bill. [47 New Pro-Life Laws Enacted in US; PNCI Global News_Dec 22, 2015] US: Bill Authorizing Adult Stem Cell Treatments The US Congress has passed the Stem Cell Therapeutic and Research Reauthorization Act (HR 2820), reauthorizing programs that utilize adult stem cells and cord blood stem cells to treat a range of diseases in adults and children. Passage ensures the adult stem cell programs will be funded through 2020, and the C.W. Bill Young Cell Transplantation Program and National Cord Blood Inventory will be funded for another five years. “It remains one of the best kept secrets in America that umbilical cord blood stem cells and adult stem cells in general are curing people of a myriad of terrible conditions and diseases in adults as well as children. “Cord blood, which was once seen as medical waste, is now making miracles,” said bill sponsor Rep. Smith. HR 2820 was championed...

Chicago Woman Is First Adult Cured Of Sickle Cell Disease With Chemo-Free Technique

Ieshea Thomas, a Chicago woman, is the first adult to be cured of sickle cell disease with the chemotherapy-free procedure at UI Hospital. Iesha Thomas has been in and out of hospitals battling sickle cell disease since she was only 8 months old. This summer, 33-year-old Thomas became the first adult to be cured of sickle cell disease with a chemotherapy-free procedure at University of Illinois Hospital & Health Sciences System (UI Health), the University reported. Thomas is one of 12 adult patients cured of sickle cell disease as part of a clinical trial at UI Health that used a unique procedure for stem cell transplantation from healthy tissue matched from a sibling donor. Findings from phase I/II of the clinical trial are published online in the journal Biology of Blood & Marrow Transplantation. A Less Harsh Treatment Stem cell transplants have been used for years as a means of possibly curing sickle cell disease. However, before the stem cell transplant could be completed patients would have to endure a taxing course of drugs to kill the cancer cells, otherwise known as chemotherapy. The more traditional form of stem cell transplant uses chemotherapy to destroy the patient’s own bone marrow, which shuts down their immune system and makes them vulnerable to infections. The new technique – first developed and performed at the National Institutes of Health campus in Maryland – eliminates the need for chemotherapy to prepare the patient to receive the transplanted cells and offers the prospect of cure for tens of thousands of adults suffering from sickle cell disease – many of them Black Americans. According to...

Boston Children’s Hospital Has Been Using Brains of Aborted Children in Research for Years

Research Using Aborted Baby Organs & Tissues Will Phase Out — Not As Successful as Advanced Stem Cell Technology, and Not Needed to Produce New Cell Lines for Vaccines In 2008, scientists at Boston Children’s Hospital started using brains of aborted babies for research. The Boston Globe reports that Harvard neuroscientist, Emi Takahashi, examines fetal brain tissue in hopes to better understand neurological disorders such as epilepsy, autism and schizophrenia. Although Takahashi is aware of the current controversy regarding fetal “tissue” research and Planned Parenthood, she says the issue is not about morality or abortion; instead, it’s about science. She explained, “It’s purely a scientific issue, not a moral one.”  [ed. and her words make it so…] In July, Takahashi received a call from an officer at the National Institutes of Health inquiring about her study of fetal brain development because she received a grant to study 30 fetal brains. Takahashi explained, “She was wondering how I would get that many samples. Congress was asking her what was going on with my research, and she wanted to make sure I wasn’t obtaining them illegally.” The officer was concerned because eight undercover videos released by The Center for Medical Progress indicate that Planned Parenthood affiliates profit from aborted babies’ body parts, alter procedures to obtain salable organs and deliver babies “fully-intact” to procure “high-quality specimen.” All of these activities are illegal, and the videos raise serious questions about the organization’s intentions. Currently, Takahashi scans fetal brains, examines computerized 3-D images of them and uses a computer program to reconstruct fiber pathways in the brain. The researcher claims she obtains the...

Scientists Say Aborted Babies are ‘Essential for Research’, Yet No One Has Ever Been Cured

[Comment: Although the mainstream media continues to downplay or ignore the issue, the defense of using aborted babies’ body parts is unraveling. N. Valko RN, 16 Aug 2015] Scientists Say Aborted Babies are “Essential for Research,” Yet No One Has Ever Been Cured With the exposure of Planned Parenthood’s activities in procuring aborted babies for scientists, the media is buying into the lie that this is “life-saving” research. In a recent article picked up by the AP and published in US News, the hysterics were evidenced by the headlines “Amid uproar over anti-abortion videos scientists say fetal tissue essential for research”. The article starts out sounding like talking points for Planned Parenthood’s Cecile Richards by quoting from Stanford University spokesperson Lisa Lapin: “If researchers are unable to work with fetal tissue, there is a huge list of diseases for which researchers would move much more slowly, rather than quickly, to find their cause and how they can be cured.” Not only has there never been a cure for any disease whatsoever using aborted fetal material, the very next sentence demonstrates what’s really behind their motives. “From 2011 through 2014 alone, 97 research institutions – mostly universities and hospitals – received a total of $280 million in federal grants for fetal tissue research from the National Institutes of Health.” Cha-ching! Looks like government defunding of Planned Parenthood is only the tip of the iceberg, isn’t it? Next the article notes that vaccines for hepatitis A, German measles, chickenpox and rabies were developed using cell lines grown from tissue from elective abortions. “What they fail to admit is that with the...

April – February 2014: Stem Cell & Cloning Research

    NEW! Amazing New Spinal Cord Implant Revives Legs of 4 Paralyzed Men Save a Baby’s Life, Save Two Lives with Umbilical Cord Blood Error Eventually Promotes Truth …  [Ed. While this is actually not a stem cell success, it is a regenerative success, nonetheless!] Amazing New Spinal Cord Implant Revives Legs of 4 Paralyzed Men Improvement is generally thought of in a positive light. Medical technology has improved to help people’s lives in all sorts of ways… Four men who were completely paralyzed below the waist are now able to move their legs, toes and lift up to 100 kilograms with their legs. These men are part of a group who have received electrical implants which have “reawakened” their spinal cords. New Scientist explains how the breakthrough technology works: The device – an array of electrodes – is implanted not at the point of injury, but in the still intact lumbosacral region of the spinal cord, which is the main information hub linking the brain to the lower limbs. Despite being crushed, Angeli says, the spinal cord and its associated nerve connections retain huge capacity to continue sending messages.   …     Angeli says the implant restores what in healthy people would be the resting potential of the spinal cord – the baseline electrical activity that keeps the cord alert, but which wanes through lack of use in people who are paralysed.     Once this background electrical impetus is restored artificially, the cord reawakens and can register the brain’s “intent” to move and convert this into fine movement at the motor neuron level. And by modulating the voltage...

November – January 2013: Cloning & Stem Cell Research

     FIND PAST HOMEPAGE TOPICS UNDER "CURRENT HEADLINES" IN THE LEFT MENU…    NEW! Once-Paralyzed Man Given New Lease on Life Thanks to Adult Stem Cells NEW! Adult Stem Cell Research Has Defeated Embryonic Stem Cells for Funding Priorities Down Syndrome Reversed in Newborn Mice with Single Injection Human Trials With Ethical Induced Pluripotent Stem Cells Start Soon What is HeLa? Possible HIV “Cure” is a Victory for Adult Stem Cell Research — http://www.lifenews.com/2013/07/05/possible-hiv-cure-is-a-victory-for-adult-stem-cell-research/ Adult Stem Cells Could Help Amputees With Limb Regrowth Commentary: Two-Year-Old Emerges From “Vegetative State” After Adult Stem Cell Treatment: Another Reason to End the Deliberate Inhumane Killing of the Brain Injured Toddler Gets Windpipe Grown From Her Own Stem Cells Scientists Clone and Kill Human Embryos for Dubious Research / Scientists Claim They Have Cloned Human Embryos for Stem Cells New Human Cloning Research Exploits Women, Destroys Human Life Unethical Scientists are Making Human-Animal Hybrids, Again Somatic Cell Nuclear Transfer IS Human Cloning Not With a Bang, But a Whimper: the Quiet Demise of Embryonic Stem Cell Research Confused About Stem Cell Research? Another Pro-Life Primer Soccer Stars Saving Ethical Umbilical Cord Stem Cells for Future Needs Scientists Make Brain Cells From Sloughed-off Kidney Cells Found in Human Urine… Once-Paralyzed Man Given New Lease on Life Thanks to Adult Stem Cells Here is the latest in the many stories we’ve carried about the remarkable improvements in patients who have been treated not with embryonic stem cells (there have been no such improvements) but with ethically unobjectionable adult stem cells which are obtained from bone marrow, blood, fat tissue, umbilical cord blood, and other...

December – January 2012: Stem Cell Research

FIND PAST HOMEPAGE TOPICS UNDER "CURRENT HEADLINES" IN THE LEFT MENU…   www.stemcellresearchfacts.org   Adult Stem Cell Research Pioneers Deserve More Attention Nose Cells Help Dogs Walk Again After Spinal Cord Injury California Panel Awarded Stem Cells Grants to Its Directors Adult Stem Cells from Blood to Cure Wrinkles Scientists Continue Trend Towards Adult Stem Cell Research Stem Cell Bank Closes as Embryonic Research 'Dies Off' Report: Stem Cell Research Debate Over, Embryonic Side Lost Skin Cells From Heart Failure Patients Made Into Healthy New Heart Muscle Cells Adult Stem Cell Treatments Move Ahead, Embryonic Stem Cells Fall Farther Behind Commentary: Embryonic Stem Cell Researcher Resigns, Fabricated Experiment Adult Stem Cells Make New Blood Vessels for Heart Really Bad News: FDA Permits Use of Fetal Brain Tissue in Lab Experiments The Heart of Life Komen: Embryonic Research Has “Not Shown Promise” for Breast Cancer, Yet Funding Continues Embryonic-Like Stem Cells Have Yet To Cure Any Patients Adult Stem Cell Studies in Mice Combat Aging Effects Adult Stem Cells Use Special Pathways To Repair Damaged Muscle   COURT CASE Legal Battle Over Obama’s Embryonic Stem Cell Research Funding Moves Ahead… Adult Stem Cell Research Pioneers Deserve More Attention It was very heartening to see Dr. Shinya Yamanaka recognized with the 2012 Nobel Prize for Physiology or Medicine [1], for his work in development of induced pluripotent stem cells (iPS cells), an ethical route to create pluripotent stem cells [2]. http://www.lifenews.com/2012/11/21/adult-stem-cell-research-pioneers-deserve-more-attention/ Nose Cells Help Dogs Walk Again After Spinal Cord Injury Dogs are well known for their keen sense of smell. It turns out their noses are good for more than just...

December – October 2011: Stem Cell Research

   FIND PAST HOMEPAGE TOPICS UNDER "CURRENT HEADLINES" IN THE LEFT MENU…    Dolly Cloning Scientist Says Abandon Embryonic Stem Cell Research Ethical Stem Cell Research Shows Most Promise for Patients Geron Company Halts First Human Embryonic Stem Cell Research Trial (Commentary) / All the News that’s Fit to Forget: Why You’re Not Hearing Much About Embryonic Stem Cells These Days / How Big a Blow was Geron’s Bombshell That it is Bailing on Embryonic Stem Cell Research?   BIG. Commentary: Ethical Stem Cells May Help Patients With Osteogenesis Imperfecta Peyton Manning Has Adult Stem Cell Procedure to Treat Neck / Why Do Peyton Manning & Others Leave the USA to Procure Adult Stem Cell Treatments? Adult Stem Cells Tested to Treat ALS (Lou Gehrig’s Disease) Obama Admin OKs More Human Embryo-Destroying Stem Cell Lines & Funding, Ignores Adult Stem Cells IPS Cells May Hold Treatment for Sickle Cell Anemia More Misleading Headlines on Supposed Embryonic Advance NIH Revitalization Act & Human Embryo Use Scientists Appeal to Stop Obama's Embryo-Destroying Stem Cell Funding Direct Conversion Challenges Embryo-Destroying Stem Cell Research Adult Stem Cell Treatment May Help Unborn Avoid Premature Birth / ALTERNATE VIEW: If Amniotic Sac is Infected, Stem Cell Patch May be a Bad Idea Missouri House Defeats Pro-Life Limits on Embryo-Destructive Stem Cell Research… Scientist Who Cloned Dolly Says Abandon Embryonic Stem Cell Research Ian Wilmut, the scientist who achieved international notoriety for cloning the sheep Dolly, is now urging his fellow scientists and researchers to abandon embryonic stem cell research. His comments at a conference follow on the major news that Geron, a cloning company the Obama administration...

September – August 2011: Stem Cell Research / Human Cloning

  FIND PAST HOMEPAGE TOPICS UNDER "CURRENT HEADLINES" IN THE LEFT MENU…    Exercise Helps Adult Stem Cells Build Bone, Not Fat Commentary — Now in 2011:  Why Embryonic Stem Cells Should Not be Transplanted into a Human Being Adult Stem Cells Work Against Stress and Depression Antibody Cocktail May Lead to 'Safer' Embryo-Destroying Stem Cell Trials…? Stem Cell Breakthrough Gives Hope to Parkinson's Patients Scientists Find Another Adult Stem Cell Source: The Ear Study Shows that Collecting Bone Marrow Stem Cells by Apheresis is Safe for the Donor NIH Revitalization Act & Human Embryo Use The Demand for Death: Medical Research & Fetal Tissue Japanese Researchers Grow Mice Teeth from Adult Stem Cells New Lab-Grown Sperm from Embryo-Destroyed Stem Cells Is Not a Moral Solution to Male Infertility Perry Uses Own Adult Stem Cells for Back Surgery Treating Advanced Breast Cancer With Adult Stem Cells Induced Pluripotent Stem Cells: The Ethical Embryonic Alternative Minnesota Now Paying Scientists to Engage in Human Cloning Federal Judge Disagrees but Tosses Suit Against Tax-Funded Embryo Research / Court Rules in Favor of Taxpayer Funding for Embryonic Stem Cell Research ‘Frankenstein’: UK Scientists Warn About Secret Human-Animal Hybrid Research… Exercise Helps Adult Stem Cells Build Bone, Not Fat Canadian scientists have published data that indicate exercise stimulates adult stem cells to form bone instead of fat. The scientists used a mouse model to study exercise effects on adult bone marrow stem cell and blood production. Using treadmill-conditioned mice, they found that aerobic exercise triggers adult stem cells to become bone more often than fat. The bone environment provides better conditions, called a “niche”,...

July – April 2011: Stem Cell Research

  FIND PAST HOMEPAGE TOPICS UNDER "CURRENT HEADLINES" IN THE LEFT MENU…   NEW! Adult Stem Cells Helping Patients With Scleroderma Skin Disease NEW! Adult Stem Cell Trial in Texas Will Treat Stroke Patients Adult Stem Cell Success: Cells Relieve Heart Pain in Patients Adult Stem Cells Help Create New Windpipe, Save Cancer Patient Scientists Grow Human Heart in Lab Using Adult Stem Cells Early Trial Shows Adult Stem Cells Healing Hearts SKIN: National Geographic Program Shows Skin Gun Sprays Healing Adult Stem Cells Girl Cured of Brain Cancer Using Umbilical Cord Stem Cells Success: Human Neurons From Adult Skin Cells Good News and Bad News for Induced Pluripotent Stem Cells Immediate Success: Adult Stem Cells are Treating Thousands of Patients Now Ethical Stem Cell Research… Adult Stem Cells Helping Patients With Scleroderma Skin Disease Dr. Richard Burt and colleagues at Northwestern University have just published a new study in The Lancet that provides more evidence for the success of adult stem cell transplant in treating system sclerosis (scleroderma). The autoimmune disease causes rigidity in the skin and organs, including lungs, of its victims; it exerts its fatal influence by essentially turning them to stone. Ten patients were treated with their own adult stem cells, and all improved at or before 12 months after treatment, compared with zero of the nine patients that received cyclophosphamide, a chemotherapeutic agent considered the “standard of care” for this disease. None of the adult stem cell-treated patients had their disease worsen, while 8 of the 9 chemo-treated patients showed worsening, and eventually 7 of the chemo patients switched to the adult stem cell...

March – January 2011: Stem Cell Research

A New Stem Cell Enters: Induced Conditional Self-Renewing Progenitor Cells (ICSP) Second Chance at Life for Adult Stem Cell Transplant Patient Genetic Abnormalities Discovered Associated With The Creation Of 'iPS' Stem Cells / More Genetic Problems with Artificial Stem Cells Other Stem Cell Research Studies Incredible ‘Skin Gun’ Heals Severe Burns in Days — National Geographic “Explorer” / Amazing "Skin Gun" Heals Burn Wounds Using Victims' Adult Stem Cells / Building a Beating Heart / Extra Cellular Matrix How Nasal Stem Cells Might Prevent Childhood Deafness Babies Can Be Treated With Adult Stem Cells, Even in the Womb — "Now We Can Really Think Big!" Artificially Produced Stem Cells May ‘Hold On’ to Genetic Past – Problematic Mitochondrial DNA Integrity Is Essential For Mitochondrial Maturation During Differentiation of Neural Stem Cells Adult Stem Cells Helping Women With Breast Reconstruction Obama Admin OKs Another Human Embryonic Stem Cell Trial Time To End the CA Stem Cell Institute Adult Fat Cell-Derived Stem Cells Useful in Tissue Reconstruction Adipose-derived stem cells maintain their "stemness" and could be useful for cell-based therapies. A team of researchers from several institutions in Italy isolated and characterized adult fat cell-derived stem cells from patients undergoing lipoaspiration (surgical removal of fat deposits) in order to investigate the ability of the fat cells to maintain their stem cell characteristics in in vitro cultures to the point where once transplanted they could aid in tissue regeneration… A New Stem Cell Enters the Mix: Induced Conditional Self-Renewing Progenitor Cells   In the past few months, a slew of papers have indicated that the therapeutic potential of a promising type of...

Wound Healing: Extracellular Matrix (ECM)

EXTRACELLULAR MATRIX  ECM The extracellular matrix (ECM) is a complex structural entity surrounding and supporting cells that are found within mammalian tissues. The ECM is often referred to as the connective tissue. The ECM is composed of 3 major classes of biomolecules: 1. Structural proteins: collagen and elastin. 2. Specialized proteins: e.g. fibrillin, fibronectin, and laminin. 3. Proteoglycans: these are composed of a protein core to which is attached long chains of repeating disaccharide units termed of glycosaminoglycans (GAGs) forming extremely complex high molecular weight components of the ECM. Proteoglycans are covered in the section on Glycosaminoglycans and Proteoglycans. [http://themedicalbiochemistrypage.org/extracellularmatrix.html] Key Points    1. The extracellular matrix (ECM) is the largest component of normal skin and gives the skin its unique properties of elasticity, tensile strength and compressibility.    2. In acute wounds the provisional wound matrix, containing fibrin and fibronectin, provides a scaffolding to direct cells into the injury, as well as stimulating them to proliferate, differentiate and synthesise new ECM.    3. Chronic wounds contain increased levels of inflammatory cells, giving rise to elevated levels of proteases that appear to degrade the ECM components, growth factors and receptors that are essential for healing.    4. Understanding of the importance of re-establishing a functional ECM in chronic wounds has led to technical advances and the development of products that reduce excessive protease levels or contribute functional ECM proteins, thereby facilitating the healing process. Abstract The extracellular matrix (ECM) is the largest component of the dermal skin layer and the synthesis of ECM is a key feature of wound healing, especially when there has been a significant loss of...

December – October 2010: Stem Cell Research & Funding Battles

FIND PAST HOMEPAGE TOPICS UNDER "CURRENT HEADLINES" IN THE LEFT MENU…   Doctors Say Adult Stem Cell Research Cures HIV-Positive Man Scientists Create Cloned Mice With Two Genetic Fathers California's Stem Cell Research Agency Faces Strong Criticism Leukemia Patient Completely Cured with Cord Blood Stem Cells Parents: Cord Blood Stem Cells Significantly Improved Cerebral Palsy Symptoms Direct Conversion May Make Embryonic Stem Cell Research Obsolete U.S. House Re-approves Funding for Ethical Cord Blood Stem Cells Major Scientific Advance: Blood From Skin Without Stem Cells Cult of Celebrity Drives Research, Leaves Ethical Researchers in the Cold: Stem Cell Pioneer Media Misreporting: Embryonic Stem Cells Not Involved in Geron's New Testing California Funds Less Embryonic, More Adult Stem Cell Research Adult Stem Cell Research Far Ahead of Embryonic Adult Stem Cells Hammer the Sickle Commentary: Best Kept Secret of Adult Stem Cells — They Are Treating Multiple Sclerosis Adult Stem Cells: More than Meets the Eye? Geron Company Claims First Patient Treated With Embryonic Stem Cells, Not The Case If Only Liberals Had a Heart for Adult Stem Cells Commentary: Stem Cell Research is the Best-Kept Secret in the Galaxy Scientists Ask Appeals Court Not to Allow Federal Funding of Research Involving the Destruction of Living Human Embryos Pending the Government's Appeal of the District Court's Funding Ban Scientific Studies Using Adult & Induced Pluripotent Stem Cells NIH Expedites Grants for Human Embryo Destroying Research  Stem Cell Financing Ban Ends, for Now Good News in the Midst of Bad Legal Battles Over Funding: 5-Year Reauthorization of the National Cord Blood Inventory Program Passes in the US House New iPS Technique for...

Recent Adult Stem Cell Research Educational Campaign — www.stemcellresearchfacts.org

Recent Adult Stem Cell Research Educational Campaign — www.stemcellresearchfacts.org With the never-ending battles over abortion and health care, the pro-life community may be lulled into forgetting that other fights exist on the bioethics front. To keep those concerns at the forefront, the Family Research Council is launching a new adult stem cell research educational campaign. "It's no longer a dream," FRC tells LifeNews.com. "Now there's living proof that adult stem cell treatments are creating medical miracles for cancer, blood diseases, immune disorders, and heart damage." Last November 2009, FRC gave the public and pro-life advocates in the Kansas City area a chance to meet patients who are living miracles through its new Adult Stem Cells Saved My Life campaign. The event took place at noon at the Shawnee Town Hall in Shawnee, Kansas. The choice of Kansas City as the location of the launch of the new campaign is not an arbitrary one. It has become ground zero in the embryonic stem cell research and human cloning battles. "The Kansas City metropolitan area has become one of the strategic centers in the Midwest for the life sciences, including Adult Stem Cell and cord blood research and treatments," FRC notes. "Between St. Luke's Hospital, Children's Mercy Hospital, and the University of Kansas Medical Center, these pioneering treatment centers have treated over 1,500 patients with adult stem cells." It is also the location of the Stowers research institute, where scientists are destroying human beings at their earliest stages for embryonic research that has never passed significant hurdles in animals to even be tried in human patients. Missouri was also the location...

January 2010: Stem Cell & Cloning Research

Pioneering Adult Stem Cell Treatment Helps Man Recover Sight After 15 Years Australia Man With MS Walks Again After Adult Stem Cell Treatment  Newly Added Articles: Reprogramming a Patient's Eye Cells May Herald New Degenerative Disease Treatments Spraying on Skin Cells to Heal Burns: A new technique in burn treatment provides an alternative to skin grafts in the operating room Treating Heart Disease With a Person's Own Stem Cells… Reprogramming a Patient's Eye Cells May Herald New Degenerative Disease Treatments Scientists have overcome a key barrier to the clinical use of stem cells with a technique which transforms regular body cells into artificial stem cells without the need for introducing foreign genetic materials, which could be potentially harmful. The research, published in Stem Cells, suggests that cells taken from a patient's eye can be "reprogrammed" to replace or restore cells lost to degenerative diseases. The research, led by Professor Iqbal Ahmad and co-authors from the University of Nebraska Medical Center, is the first proof in principle that somatic, or body cells, can be reprogrammed into induced pluripotent stem cells (iPSCs) simply through the influence of the microenvironment in which the sampled cells are cultured. Until now genetic materials were introduced into somatic cells to re-programme them to become pluripotent, enabling them to generate cells of all three embryonic lineages. "Our findings provide evidence for an emerging view that somatic cells may be reprogrammed safely and simply by defined chemicals and other factors, which may facilitate their clinical use," said Ahmad. "The next step is to know how robust the reprogramming is and what existed within the microenvironment to cause...

Scientists Cure Sickle Cell Anemia in Mice (UAB, Whitehead 2008)

Scientists Cure Sickle Cell Anemia in Mice: Adult Skin Cells Coaxed to Produce Embryonic-like Properties Published in UAB Insight, Winter 2008 A team of scientists from UAB and the Whitehead Institute for Biomedical Research have cured mice with humanized sickle cell anemia using a method that involves reprogramming skin fibroblasts to an embryonic-stem-cell-like state. This process, which does not involve the use of embryos, is the first proof-of-principle in animals of a therapy using induced pluripotent stem (iPS) cells (Science. 2007;318:1920-1923). The iPS cells have many of the same critical properties that have made embryonic stem cells the focus of intense research. “The iPS cells express a number of the key genes expressed by embryonic stem cells, can be converted into virtually any cell type — brain, blood, lung, and liver, for example — and can divide to make more cells with the same attributes,” says UAB Department of Biochemistry and Molecular Genetics Chair Tim M. Townes, MD, coauthor of the Science paper. “Like embryonic stem cells, iPS cells hold tremendous therapeutic promise. Once skin cells are converted to iPS cells, we can correct disease-causing mutations in vitro and transplant corrected cells back into the body where they start generating normal cells,” he says. This scenario is precisely what the UAB/Whitehead Institute team achieved with the sickle cell mouse models, and Townes believes that adapting the technique for use in humans is only a matter of time. The technique used to create iPS cells, which hold vast therapeutic potential, avoids the ethical storm surrounding embryonic stem cell work. “The process of generating iPS cells bypasses creation of a blastocyst...

Notes on Cloning by Embryo Splitting (2009)

From the files of Dr Dianne Irving ….. FYI — short list of references from studies recently published in PubMed concerning the endorsement and use of cloning by "embryo splitting" as "infertility treatments, and the push by lawyers to change and deconstruct the critical and accurate scientific terms of human embryology in law for "new practices and new times".  With these new fabricated "scientific" terms, the public won't even be able to tell what kinds of human embryo research, human cloning, human genetic engineering, or "infertility treatments" they are doing any more.  Please pass on to interested others.  The term "abortion" no longer involves only sexually reproduced human embryos, and the term "cloning" no longer involves only the SCNT cloning technique.   In fact, neither have been true for some time now. — DNI     —  “Embryo-splitting” endorsed for “infertility treatments: The American Medical Association has recently renewed its position on the use of "embryo splitting" (i.e., a form of cloning) as infertility treatments.  FYI, I have copied the URL for this latest report, as well as the URL provided there for the original 1994 report which has been serially updated.  — DNI     Code of Medical Ethics (Sept 21, 2009) Opinion 2.145 – Pre-embryo Splitting (a summary) [[note the use of the erroneous scientific term “pre-embryo”]] http://www.ama-assn.org/ama/pub/physician-resources/medical-ethics/code-medical-ethics/opinion2145.shtml This Report provides a hyperlink to the original 1994 report that explains “blastomere separation” and “blastocyst splitting” in IVF facilities for “infertility treatments”: CEJA Report 1-I-94 Recent medical developments have enabled scientific researchers to split human pre-embryos into genetically identical sibling embryos.  …  The first two techdniques involve the...

December – September 2009: Stem Cell & Cloning Research

13 Human Embryonic Stem Cell Lines Approved for Research by NIH Adult Stem Cell Resources – http://www.stemcellresearchfacts.org/ Cord Blood Stem Cells Treat Cerebral Palsy University of Nebraska Regents Defeat Effort to Limit Embryonic Stem Cell Research Human Trial of Embryonic Stem Cell Research Stopped Due to Animal Problems / FDA Delays Geron's Human Embryonic Stem Cell Research Trials, Seeks Data Suit Filed Against NIH to Stop Federal Funding of Destructive Embryo Research South Korea Seeks Prison Term for Stem Cell Research Fraud Hwang Woo-suk… Thirteen Embryonic Stem Cell Lines Approved for Research by NIH Thirteen embryonic stem cell lines were approved Wednesday for federally-funded research with assurance from the director of the National Institutes for Health that research on them is ethical and does not violate principles on human dignity and sanctity of life. “Let me be clear, these are embryos that would have been otherwise discarded as part of in-vitro fertilization clinic activities,” Dr. Francis Collins noted during an appearance Wednesday on CNN. [Ed. apparently, that makes it OK to do research on these human embryos — kill them for the sake of research rather than just killing them… Sounds rather like the rationalization used during the Nazi Regime — use them for medical research since they will be killed anyway…] The NIH director also noted that his federal agency had conducted a “very careful” review of the lines based on the conditions that were set forth in guidelines issued earlier this year and further pointed out that it was former President Bush who first approved the use of stem cell lines for federal researchers to work with....