Stem Cell – Archive

May 2006: Stem Cell & Cloning Research

Hwang's Embryonic Stem Cell Research Used More Human Eggs Than Claimed ESCR Backers Spend Milliions NJ Gov to Push Lawmakers on ESCR Bill WI Lawmaker Wants ESCR Separate at UW from other research American Scientists Announce Intent to Clone Humans for Research China bans sale of human eggs, tightens control over sperm banks to boost control over the nation's rapidly expanding fertility business HWANG'S EMBRYONIC STEM CELL RESEARCH USED MORE HUMAN EGGS THAN CLAIMED. While news that the South Korean government had indicted embryonic stem cell researcher Hwang Woo-suk and his colleagues on charges of fraud and embezzlement, the government's report also revealed Hwang's team used 5 times more human eggs in their research than they claimed.  The news is disturbing to bioethics observers because people on both sides of the stem cell research debate are concerned that egg donations take advantage of women, especially, the poor, and can lead to coercion. Government prosecutors found Hwang's team used 2,236 ova taken from 136 women between November 2002 and December 2005. The donations came from four medical institutions: Hanyang University Medical Center, fertility clinic MizMedi Hospital, Jeil General Hospital and Hanna Women's Clinic. The number is far more than the 427 eggs Hwang's team claims to have used. [Korean Times; 16May06, LifeNews.com] ESCR BACKERS SPEND MILLIONS. Meanwhile, backers of an initiative that will likely appear on the November ballot to promote embryonic stem cell research and human cloning are spending heavily on their campaign to get it approved. New campaign finance reports reveal the Missouri Coalition for Lifesaving Cures raised more than $2.5 million in the last three months to promote...

June 2006: Stem Cell & Cloning Research

Doctors Call Adult Stem Cells a "Cure" for Incontinence Why Embryonic Stem Cell Research? DOCTORS CALL STEM CELLS 'CURE' FOR INCONTINENCE in the vast majority of patients who were treated with injections of their own stem cells. The finding, which was presented 28May06, is the latest accomplishment in a promising area of research: using adult stem cells derived from patients' own muscle tissue to treat a troubling condition that affects more than 15 million Americans. The researchers described the treatment as a cure, meaning the patients did not need to wear absorbent pads after they were treated. "It's highly effective and it's much more effective than we previously thought," said Hannes Strasser, lead author of the study. "If somebody had told me it would have worked so well four years ago, I would not have believed it." Some of the first patients to undergo the technique remained continent four years after the treatment, said Strasser [assoc prof, urology,  Medical University of Innsbruck, Austria]. The results involved 186 men and women ages 36 to 85. The study involved about twice as many women as men. One year after the treatment, 153 of those treated did not need to wear pads, Strasser said. In addition to curing the incontinence, the patients also had a dramatically improved quality of life, he said. There were no side effects, although a later patient, one of 270 who now have undergone the therapy, suffered a perforation of the urethra during the treatment. The research was presented at the American Urological Association annual meeting in Atlanta. One potential advantage to the stem cell treatment is the...

April 2006: Stem Cell & Cloning Research

Hwang Did Clone Snuppy Hair Follicle Stem Cells Schatten May Have Stolen Stem Cell Research Technology CA ESCR Moving Forward With $14M From Bonds Sales Complete Bladders Grown From Patients’ Own Cells US Researchers Also Find Embryonic-Like Stem Cells in Testicles HWANG DID CLONE SNUPPY. Although So. Korea’s Hwang was found to have fabricated almost all cloning and ESCR , “exhaustive investigation has determined that they did successfully clone Snuppy”, the world’s first cloned dog, from ear skin cells of an Afghan dog. “Nearly 100,000 dog embryos were created and transferred into 123 surrogate female dogs. Ultimately, only 3 pregnancies survived. One died in miscarriage; a second died 22 days after birth…This incredibly large mortality percentage is another reason” to avoid cloning humans. [J. Willke, MD, Cincinnati Right to Life, 3/06] HAIR FOLLICLE STEM CELLS. The firm Anti-Cancer has used hair follicle stem cells to repair nerve damage in mice. These stem cells are readily obtainable, and according to the research report, would provide “an ethically superior alternative to fetal and embryonic stem cells.” [J. Willke, MD, Cincinnati Right to Life, 3/06] SCHATTEN MAY HAVE STOLEN STEM CELL RESEARCH TECHNOLOGY From Hwang Woo-suk.  South Korea KBS television station is alleging that Univ of Pittsburgh scientist Gerald Schatten stole cloning and stem cell research technology for use in his own efforts to obtain American patents for the research “… in the United States for a technology needed for nuclear transfer of animal somatic cells, about nine months ahead of Hwang,” Moon said. Moon told the Times that South Korea is required to ask the U.S. government not to issue the...

March 2006: Stem Cell & Cloning Research

Adult Stem Cell Research Shows Strong Results for Diabetes Patients Clinical Trial to Test Ethical Stem Cells for Pediatric Brain Injuries Putting Adult Stem Cells in Failing Hearts Cells from Aborted Babies Transplanted into Brains of Huntington’s Patients ADULT STEM CELL RESEARCH SHOWS STRONG RESULTS FOR DIABETES PATIENTS. Yet another treatment for diabetes is showing promising results, without the use of embryonic stem cells. Researchers at the University of Minnesota have successfully used islet cells from pigs to reverse the course of diabetes in monkeys. While the technique remains experimental, farms are already being created to raise specially bred pigs for clinical trials. “This is a very critical milestone in our ability to provide tissue for transplants on an unlimited basis,” said Dr. Bernhard Hering, lead investigator of the research. To date, no clinical trials for embryonic stem cell research have been performed on humans, as no proof of their benefit has been discovered. [LifeNews.com, 5Mar06] CLINICAL TRIAL TO TEST ETHICAL STEM CELLS FOR PEDIATRIC BRAIN INJURIES. A study to examine stem cell therapy to treat children’s brain injuries will begin this year at the University of Texas Medical School at Houston and Memorial Hermann Children’s Hospital in Houston. Researchers will assess the safety and potential of treating traumatic brain injuries in children with stem cells derived from the children’s own bone marrow. This study is the first to test stem cell therapy for traumatic brain injury, the scientists said. The phase I clinical trial of 10 patients, ages 5 to 14, will build on previous laboratory and animal research that indicated that bone marrow-derived stem cells can migrate...

Another Adult Stem Cell Breakthrough: Lupus Successes (2/06)

A young woman and lupus sufferer is praising a new Adult Stem Cell treatment that she credits with giving back her life. Edjuana Ross, now 33, was diagnosed with the autoimmune condition known as systemic lupus erythematosus – Lupus for short – soon after graduating from high school. She was one of 48 people who received the experimental therapy – a stem-cell transplant from her own bone marrow. Ross said she has been in remission since recovering from her stem cell treatment done in 2003. “I’m just trying to get used to being well, and it’s a very weird feeling,” she said [Associated Press report]. Thirty-three of the 48 patients with lupus who received the groundbreaking treatment from Chicago’s Northwestern Memorial Hospital have been symptom free ever since. Ross and the others in the experimental group were among approximately 5% of lupus sufferers who have a form of the disease that responds poorly to standard therapy. The autoimmune process attacks vital organs such as the heart, brain, and kidneys, and can be fatal. The most common treatment, prednisone, also causes numerous side effects such as thinning bones and weight gain – high doses in Ross’s case also left her with diabetes. Lead researcher in the study, Dr. Richard Burt, said he was pleased with the outcome. “It turned out very well, showing that we could do this safely,” he said. Lupus afflicts about 1.5 million Americans, 90% of them women. Ross said that since the treatment she feels “110 percent better,” and that she looks forward to completing a master’s degree. “It gave me my life back,” she said....

January 2006: Stem Cell & Cloning Research

Research of Korean Embryonic Stem Cell Scientist Declared “Intentionally Fabricated” Adult Stem Cell Research Discovery May Change Entire Debate U.S. Congress Passes $300 Million+ Umbilical Cord Blood Stem Cell Bill – President Bush Signs It 20Dec05 Ian Wilmut wants to Experiment with ESCs on Dying Humans Singer Don Ho Treated with Adult Stem Cells for Heart Problems… RESEARCH OF KOREAN EMBRYONIC STEM-CELL SCIENTIST DECLARED “INTENTIONALLY FABRICATED”. The research of Korean embryonic stem-cell scientist Hwang Woo-suk has been declared “intentionally fabricated” by a panel of scientists at Seoul National University, 23Dec05. “Based on these findings, data in the 2005 Science journal cannot be regarded as a simple accidental error but as intentional fabrication made out of two stem cells,” the investigators reported. “This is a serious wrongdoing that has damaged the foundation of science.” The once national hero said, “I sincerely apologize to the people for creating shock and disappointment”. [BBC; SEOUL, 23Dec05, LifeSiteNews.com]. Hwang resigned:  “As a symbol of apology, I step down as professor of Seoul National University.” Despite admissions from Hwang’s colleagues that the embryonic stem cell research was faked and the SNU probe confirmed it, Hwang was still defiant 23Dec saying that he did produce patient-specific cells [LifeNews.com, 24Dec05]. Prof of veterinary medicine Hwang Woo Suk’s unregulated attempts to clone a human being were hit with ethics charges from American scientist Dr. Schatten [Univ Pittsburgh] who quit Hwang’s team, following disclosure of coercion in obtaining eggs for money from young female researchers. Hwang’s associate, Dr. Roh Sung-il, said that Hwang pressured scientists in the lab at Mizmedi Hospital to fake project data. Corruption is an inextricable...

Adult Stem Cell Pluripotency (update)

From the Family Research Council see www.stemcellresearch.org This page of research studies strictly details those projects published in peer-reviewed journals that are studying the PLURIPOTENCY of adult stem cells, that is, the ability of NON-embryonic stem cells to change into other types of tissue cells. In the past, this ability was only attributed to embryonic stem cells (a human embryo is destroyed to produce these stem cells). MYTH: Adult stem cells are not as versatile as embryonic stem cells. FACT: Numerous studies now demonstrate that some adult stem cells are as flexible as embryonic stem cells: 1. German scientists have shown that stem cells from adult mouse testis show embryonic stem cell-like properties, expressing genes for pluripotency (Oct-4, nanog) and forming tissues from the 3 representative tissue types of the body. An American company has announced that they can isolate such cells from mouse and adult humans. Guan K et al., Pluripotency of spermatogonial stem cells from adult mouse testis, Nature 440, 1199-1203, 27 April 2006; Kanatsu-Shinohara M & Shinohara T, The germ of pluripotency, Nature Biotechnology 24, 663-664, June 2006; Cyranoski D, Stem cells from testes: could it work?, Nature 440, 586-587, March 30, 2006. 2. Researchers in Kansas demonstrated that stem cells from the umbilical cord express pluripotency genes Oct-4, Sox-2, and nanog and show properties of “primitive pluripotent stem cells.” Carlin R et al., Expression of early transcription factors Oct-4, Sox-2 and Nanog by procine umbilical cord (PUC) matrix cells, Reproductive Biology and Endocrinology 4:8, doi:10.1186/1477-7827-4-8, 6 February 2006. 3. Scientists at the University of Minnesota Medical School have verified that umbilical cord blood stem cells...

Winter 2005: Stem Cell & Cloning Research (Update!)

Research of South Korean Embryo-Destructive Stem Cell Scientist Declared “Intentionally Fabricated” Embryonic Stem Cell Lines Prior to 8/01 Could Develop Cancer Sex-Selection by Embryo Screening Approved for US Trial Long-Term Results in Adult Stem Cells Very Positive Adult Stem Cells Derived from Heart Cells Can Repair Heart Damage The research of Korean embryonic stem-cell scientist Hwang Woo-suk has been declared “intentionally fabricated” by a panel of scientists at Seoul National University. “Based on these findings, data in the 2005 Science journal cannot be regarded as a simple accidental error but as intentional fabrication made out of two stem cells,” the investigators reported. “This is a serious wrongdoing that has damaged the foundation of science.” The once national hero said, “I sincerely apologise to the people for creating shock and disappointment,” after the announcement [BBC; SEOUL, 23Dec05, LifeSiteNews.com]. Hwang has resigned:  “As a symbol of apology, I step down as professor of Seoul National University.” Despite admissions from Hwang’s colleagues that the embryonic stem cell research was faked and the SNU probe confirmed it, Hwang was still defiant 23Dec saying that he did produce patient-specific cells [LifeNews.com, 24Dec05]. [prof, veterinary medicine] Dr. Hwang Woo Suk’s unregulated attempts to clone a human being were hit with ethics charges from an American scientist [Dr. Schatten Univ Pittsburgh] who quit Hwang’s team, following disclosure of possible coercion in obtaining eggs for money from young female researchers. Apparently, some of the photos of cell colonies supposedly derived from 11 patients were duplicates. [FRC, 6Dec05] Dr. Schatten demanded that his name be removed from an article he co-wrote with Hwang for the journal Science. The...

Fall 2005: Stem Cell & Cloning Research (updated)

Websites Demonstrate Adult & Umbilical Cord Blood Stem Cell Successes Adult Stem Cell Research Treats Spinal Cord Injury Patient Adult Stem Cell Research Shows Good Long-Term Results, Study Says  UK Allows Human Embryos to be Created with 2 Mothers, 1 Father (3 Parent Cells Involved) First Human “Clones” Made Without the Use of Sperm Illinois Governor Invites Missouri Embryonic Stem Cell Research Companies to Change States Adult Stem Cells Treat Cystic Fibrosis… WEBSITES ** With patient’s own cells, heart vessels and tissue show mending http://www.chron.com/cs/CDA/ssistory.mpl/metropolitan/3277225** Cord Blood – Premier Stem Cell Source http://www.viacord.com/what_why_premier_source.htm   ADULT STEM CELL RESEARCH TREATS SPINAL CORD INJURY PATIENT [Cythotherapy, (2005) Vol 7. No. 4, 368-373]. This was reported before but now has been published. Female paraplegic from an accident over 19 years ago. Scientists [Korea] report using surgery/umbilical cord blood stem cells infusion to restore feeling/mobility to her. Stunning results: motor activity was noticed -day 7; she was able to maintain an upright position -day 13. Fifteen days after surgery, she could elevate both lower legs about 1 cm. “The patient could move her hips and feel her hip skin on day 15 … On day 25 after transplantation her feet responded to stimulation…41 days after [stem cell] transplantation” testing “also showed regeneration of the spinal cord at the injured site” and below it. The scientists conclude the transplant “could be a good treatment method” for paraplegic patients. The authors note that the lamenectomy the patient received might have offered some benefit. The fact that the patient has a very old injury makes the results more dramatic. [28Sept05, WorldNetDaily.com; Wesley Smith, LifeNews.com Pro-Life News...

August 2005: Stem Cell & Cloning Research

New Harvard Research May Point to a Moral Procedure for Obtaining Pluripotent Stem Cells  Stem Cell Research Websites Adult Stem Cell Research Quietly Progressing Adult Stem Cells May Generate Oocytes (Egg Cells) Korea Doctors Use Adult Stem Cell Research to Fix Skin Damage California Embryo-Destructive Stem Cell Research Grants Still Delayed; More… For past Stem Cell Research headlines, click here.  STEM CELL RESEARCH WEBSITESClinicalTrials.gov – Amazing list of over 250 grants through NIH; at least half deal with non-embryonic stem cell research.http://www.clinicaltrials.gov/ct/search?term=%22stem+cells%22&submit=Search With patient’s own cells, heart vessels and tissue show mending http://www.chron.com/cs/CDA/ssistory.mpl/metropolitan/3277225 Check the Score  http://stemcellresearch.org/ Diseases Treated Now with Cord Blood Stem Cells:  http://www.viacord.com/what_diseases_treated.htm Why Cord Blood is the Premier Source of Stem Cellshttp://www.viacord.com/what_why_premier_source.htm NEW RESEARCH MAY POINT TO MORAL PROCEDURE FOR OBTAINING PLURIPOTENT STEM CELLS –    Scientists at Harvard have turned ordinary human skin cells into embryonic-like stem cells – known as pluripotent stem cells – using a new reprogramming process. The scientists’ findings are set to be published in the next edition of the journal Science and if the method proves successful it may pave the way for production of pluripotent stem cells without destroying human embryos. Two prominent opponents of embryo-destructive research say that the new procedure is not without problems but both agreed the findings represent a step in the direction of ethical stem cell research. Scientists at the Harvard Stem Cell Institute, according to a press release from the organization, fused “an entire skin cell to an existing embryonic stem cell. The result is a hybrid cell with two sets of genetic material, one from each parent. . . . [T]hey found that...

July 2005: Stem Cell & Cloning Research

Wharton’s Jelly Holds Very Pluripotent Cells Ethical Alternative for Obtaining Embryonic-LIKE Stem Cells Gains Support Japanese Scientists Cure Renal Failure with Adult Stem Cells Adult Stem Cell Research Quietly Progressing Boston Doctor Uses Stem Cells from Amniotic Fluid to Repair Birth Defects For past Stem Cell Research headlines, click here. WHARTON’S JELLY HOLDS VERY PLURIPOTENT CELLS – Dr. Curtis Cetrulo of Tufts University reported at the January 2005 AAPLOG meeting in Tampa that very early “Jell Cells” which had migrated to the placenta & then to the embryonic liver to set up blood production get stuck in the Wharton’s Jelly of the umbilical cord [Day 13.5], and so are “frozen in time”, retaining their very pluripotent – possibly totipotent – status. Using these cells in conjunction with umbilical cord blood stem cells, should produce a “dynamite” therapy combo. ETHICAL ALTERNATIVE FOR OBTAINING EMBRYONIC-LIKE STEM CELLS GAINS SUPPORT – a group of influential scientists and ethicists have proposed an ethical way to produce morally acceptable embryo-like stem cells. A new proposal for obtaining embryonic-like stem cells has received the backing of a number of influential scientists and ethicists who are opposed to embryo-destructive research. They say the method, if successful, would bypass the creation of an embryo and would go straight to creating the stem cells themselves. The proposal could serve as an answer to the demands of those in the scientific community who have touted embryonic stem cells as a potentially revolutionary cure for a bevy of diseases while also answering the concerns of those who oppose embryo destructive research.   Thirty-five scientists and ethicists signed on to a joint statement about...

June 2005: Stem Cell & Cloning Research

Pharmaceutical Scientists Promote Adult Stem Cells as Successful Therapies Without Controversy Boston Doctor Uses Stem Cells from Amniotic Fluid to Repair Birth Defects Adult Stem Cells Used to Cure Blindness South Korean Scientist Helps 64 Patients Finds Success With Adult Stem Cells Also visit Stem Cells in the left menu bar, & www.stemcellresearch.org for more information… To find last month’s Stem Cell topics, click Current Headlines in the left menu bar, and then click Stem Cell Research/Cloning. For earlier items and archival material, click Stem Cells in the left menu bar. PHARMACEUTICAL SCIENTISTS BOAST ON ADULT STEM CELLS: “THERAPIES WITHOUT CONTROVERSY” – The use of adult stem cells promises to grow as the controversy over the use of human embryo-destructive stem cells remains a hotbed political, ethical and religious issue. At the June 2005 Amer Assoc of Pharmaceutical Scientists’ (AAPS) National Biotechnology Conference [San Francisco], embryo-destructive and adult-derived stem cells will take center stage as the nation’s leading scientists discuss how their research can be immediately applied to create therapies for cancer, muscular dystrophy, arthritis, neuro-degenerative disorders, cystic fibrosis, and bone injuries. As the nation continues to debate the ethics and efficacy of using human embryonic stem cells, scientists will demonstrate how the use of adult stem cells has opened the door to groundbreaking therapies including the use of muscle stem cells for arthritis and umbilical cord blood for leukemia. “Since the first bone marrow transplant was carried out more than 30 years ago, non-embryonic stem cells have been used effectively to benefit and save thousands of lives,” said Gary S. Friedman, M.D., F.A.C.P. [dir, Ctr for Regenerative Medicine, Morristown,...

May 2005: Stem Cell Research

Dramatic Uses for Adult Stem Cells – Bibliography Adult Stem Cells to be Tested in Repairing Human Heart Muscle For the first time, scientists will be able to see whether injections of bone marrow stem cells can actually help rebuild weakened human heart muscle. Researchers at the University of Pittsburgh Medical Center will inject the cells into five to 10 heart-failure patients when the patients are implanted with a left ventricular assist device, a heart pump meant to sustain them until they can receive a heart transplant. The stem cells will be obtained from each patient’s own bone marrow… Lead investigator Dr. Amit Patel, director of cardiac cell therapy centers at UPMC and the McGowan Institute for Regenerative Medicine, said no other researchers have received approval from the FDA to use stem cells this way. According to co-investigator Dr. Robert Kormos, medical director of the McGowan Institute, the purpose of the new trial is to put stem cells into areas of damaged cardiac tissue and then, when the heart is removed to be replaced with a donor organ, see what they did. The diseased heart will be removed when a donor organ is available for transplant, perhaps six to nine months later, so the researchers will be able to see the impact of the injected cells. “No one has ever done this in the world,” Kormos said. In a study conducted in South America, he added, Patel “has already shown the hearts improved, but it’s hard to understand why.” In January, Patel presented findings from a South American multicenter study in which bone marrow-derived stem cells were injected into...

April 2005: Stem Cell Research

Adult Stem Cells Change & Repair Adult Stem Cells Repair Girl’s Skull Bone Marrow (Adult) Stem Cells Can Create Customized Skin Grafts After Burns, Breast Cancer Human Embryonic Stem Cells…     ADULT STEM CELLS CHANGE & REPAIR – ASCs are being shown in study after study to have the “multipotent” ability of embryonic stem cells, to change into many different cell types. Dr. D. Losordo research team [Tufts Univ, Boston] injected adult stem cells into the hearts of rats, that had had heart attacks. The ASCs became heart muscle, tissue cells, and blood vessels. Losordo: “I think embryonic stem cells are going to fade in the rear view mirror of adult stem cells.” [The Journal of Clinical Investigation, 2/05; [RTL Greater Cincinnati, 3/05]   ADULT STEM CELLS REPAIR GIRL’S SKULL – Metal plates traditionally were used to protect the brain in such cases. Other surgeons had failed to correct the defects, and the 7-yr-old German girl wore a protective helmet. Her brain could sometimes be seen pulsating through the missing areas of her skull. ASCs derived from her fat cells were mixed with bits of her bone and implanted over the 19 square inch area last year. The defect has been successfully corrected: The skull is now smooth to the touch, the missing parts replaced by thin but solid bone [Dr. Hans-Peter Howaldt, Justus-Liebig-University Medical School in Giessen, Germany]. “I cannot prove that our success comes from the stem cells alone,” he said, “but the combination of the two things simply worked.” Howaldt and his colleagues treated the skull in the same operation that removed bone from the girl’s...

March 2005: Stem Cell & Cloning Research

Adult Stem Cells Have “Nose” for Success VA Woman Overcoming Cancer with Adult Stem Cells Researchers in Australia have found adult nasal stem cells that can be extracted and grown easily and that can produce a wide range of specialized tissues… They obtained the adult nasal stem cells from humans aged 20-78 years old (including Parkinson’s patients) and were able to turn them into nerve, heart, muscle, and liver cells. In experiments in animals, the adult nasal stem cells produced almost every tissue. In the debate on stem cell research, we continue to hear that embryo-destructive stem cells have the “potential” to become any tissue and, so the story goes, we must kill embryos and even create new embryos by cloning to research the possible use of embryonic stem cells for disease treatment. However, not even one successful treatment on a human patient with embryo-destructive stem cells has yet occurred. Yet adult stem cells continue to show that they are the ones that can produce real results, in the laboratory and already in helping thousands of patients.  [Family Research Council, 28 March 2005] Advancements in Adult Stem Cell Research 2003/2004 Real-World Successes of Adult Stem Cell Treatments http://www.frc.org/get.cfm?i=IS04I01&f=WU05C21&t=e   VA WOMAN BEATING CANCER WITH ADULT STEM CELLS – Moira Hall, 22, has been cancer-free for a year after having been diagnosed 2 years ago with Hodgkin’s Lymphoma. She received her sister’s stem cells, and then a second transplant from her brother. Her siblings went through 5 days of shots to stimulate the cells to leave the bond marrow; then they donated blood. Moira’s immune system had to be suppressed...

February 2005: Cloning & Stem Cell Research

Australian Physician/Bioethicist Reveals Huge Profits are Motive Behind Cloning and Embryonic Stem Cell Research Push Child with Cerebral Palsy Who Could Not See or Speak Does Both Following Umbilical Cord Stem Cell Therapy CA Conflict of Interest Successful Human Treatments Already Being Performed Using Human Adult/Umbilical Stem Cells: http://www.stemcelltherapies.org/ This Webpage Gives  Ethical Stem Cell Research References: http://www.stemcelltherapies.org/stemumtherapies.htm Dr. Abboud says stem cell therapy will be a rich man’s treatment which creates a big, new industry. That, says Australian medical doctor, bioethicist and lecturer at the University of New South Wales, Dr. Amin Abboud, is the reason for the big push for embryonic stem cell research and cloning. LifeSiteNews.com interviewed the dynamic, typically Austalian, young doctor [Campaign Life Coalition,Toronto, 25Sept04] while he was on a one day stopover on the way back to Australia from conferences in Europe. The Australian bioethicist related a venture capitalist (makes risky investments for potential large profits) friend telling him, “if someone came to my office tomorrow with a cure for malaria and wanting me to invest in it, I would laugh them out of my office.” Abboud:  “Why is that? Because malaria is a poor person’s disease. It’s a disease affecting poor countries and obviously poor people can’t afford to pay for expensive drugs. But he (the friend) said I will invest in stem cell technology because it’s going to be, and it’s very important to acknowledge this, in the end stem cell therapy will be a rich man’s treatment, especially embryonic stem cell therapy. Abboud summarized, “We should never forget the financial imperatives in the whole cloning and stem cell debate and that’s why...

January 2005: Cloning & Stem Cell Research

Woman Walks Again After Umbilical Cord Stem Cell Reparation   Stem Cells May Heal Multiple Sclerosis Damage: Promising Results Seen in Lab Tests on Mice    Adult Stem Cell Research Can Improve Vision, Treat Cancer and Heart Damage   British Researchers To Attempt Liver Damage Repair Using Bone Marrow Stem Cells   New Type of Adult Stem Cell Shows Exciting Similarity to Embryonic Stem Cell Flexibility   Phenomenal Ethical Stem Cell Research   Canadian Biotechnology Expert Denounces the Creation of ‘Quasi-Embryos’ as “Morally Repugnant”   WOMAN WALKS AGAIN AFTER UMBILICAL CORD STEM CELL REPARATION – a South Korean woman, paralyzed and bedridden for 20 years, is walking again (with the help of a walking aid), 6 weeks after scientists repaired her damaged spine, using stem cells derived from umbilical cord blood (12Oct04). The South Korean research team says that this case could signal a leap forward in the treatment of spinal cord injuries. “We have glimpsed at a silver lining over the horizon,” said an excited Song Chang-Hoon, professor at Chosun University medical school. “We were all surprised at the fast improvements in the patient.” According to experts, umbilical cord blood stem cells seldom trigger negative immune response from recipients; thus, there are less problems with such transplants. On the other hand, embryonic stem cells still have immune problems and also have a tendency to develop into tumors after injection into animals or humans. In this surgery, multipotent stem cells found in umbilical cord blood were directly injected into the damaged part of Soon’s spinal cord. [“Paralyzed Woman Walks Again After Stem Cell Therapy,” Turkish Press, November 28, 2004; 1Dec04;...

Cord Blood Works To Eliminate Adult Leukemia – 2 Studies (11/04)

Umbilical-cord blood, now used mostly to treat children with leukemia, could save thousands of adults with the disease each year who cannot find bone marrow donors, two big studies indicate. A European study found that those who got cord blood were just as likely to be free of leukemia two years later as those who got marrow. A U.S. study looking at three-year survival yielded results almost as promising. To Dr. Mary Horowitz of the Medical College of Wisconsin, senior author of the U.S. study, the message is clear: Umbilical cord blood can save adults.   Leukemia patients often undergo radiation or chemotherapy to kill their cancerous white blood cells – a treatment that wipes out their immune systems, too. To restore their immune systems, doctors give these patients an infusion of bone marrow or umbilical cord blood, both of which contain stem cells capable of developing into every kind of blood cell. Cord blood offers an important advantage over marrow that makes it particularly valuable for use in transplants: Its stem cells are less likely to attack the recipient’s body. That allows a wider margin of error in matching up donors and recipients. Up to now, cord blood has been considered suitable only for children, because each donation has only about one-tenth the number of stem cells in a marrow donation. The two new studies, published in the New England Journal of Medicine, suggest that is not a serious impediment. In the European study [682 patients] about one-third of both those who got matched marrow and those who got cord blood that did not quite match their own...

October 2004: 3 Adult Stem Cell Research Articles

Adult Stem Cells Cure Italian Boy of Potentially Lethal Anemia Adult Stem Cells from Bone Marrow Can Grow Blood Vessels in Eyes Adult Muscle Stem Cells – Hope to Treat Muscular Dystrophy       The most striking questioning involved the fundamental question of when human life begins. “When quizzed by Sen. Brownback, proponents of destructive embryo research could not give a definite answer on when their own lives became of worth. When scientists don’t recognize life and its value, they have no place in research. Our culture must learn to recognize the inherent dignity of each and every human life, including the most defenseless. The alternative is a cheapening of life for everyone.”  [Senate Hearing Testimony/Witness List- http://www.frc.org/index.cfm?i=LK04I61&f=WU04I26&t=e;  Stem Cell Research, Cloning and Human Embryos http://www.frc.org/index.cfm?i=BC04C01&f=WU04I26&t=e;   FRC, 30Sept04] ADULT STEM CELLS CURE ITALIAN BOY OF POTENTIALLY LETHAL ANEMIA – An adult stem-cell therapy has cured an Italian boy of a potentially lethal anemia. The cells were gathered from the placenta of his recently born twin brothers, according to the health ministry. The innovative development in the treatment was the use of two different batches of blood from the brothers – one with plenty of stem cells, the other altered in vitro to target the older sibling’s Thalassemia. The successful stem-cell treatment spared the boy a lifetime of transfusions or a bone marrow transplant, for which an exact match would have been needed. [13Sept04, LifeNews.com] ADULT STEM CELLS FROM BONE MARROW CAN GROW BLOOD VESSELS IN EYES — Researchers [Scripps Research Inst, La Jolla, CA, headed by Dr. Martin Friedlander] have found that adult stem cells from bone marrow can target degenerating...

Treatment Combination Helps Paralyzed Rats to Walk (5/04)

In a major step forward in research on spinal cord injuries, scientists in Miami reported in May that an innovative combination of treatments allowed paralyzed rats to regain up to 70% of their ability to walk. The research is a “significant advance” that may help some of the 243,000Americans with spinal cord injuries get out of their wheelchairs. Researchers at the Miami Project to Cure Paralysis say they have found a way to promote the growth of nerve fibers in damaged spinal cords and prevent post-injury nerve death. A spinal cord injury damages the nerve circuits that carry messages from the brain to the body.Recent research has focused on transplanting cells [adult stem cells] from peripheral nerves outside the brain and spinal cord into the damaged area as a bridge across the injury. But new nerve fibers didn’t go beyond the bridge because of problems such as growth-inhibiting molecules, researcher Mary Bartlett Bunge says. Bunge, along with Damien Pearse, lead author of the study published in Nature Medicine, and colleagues, devised a three-part approach that begins shortly after the injury occurs. The research did not involve the politically sensitive issue of [embryonic] stem cells, but used cells from adult rats [adult stem cells]. Researchers first inject the rats with Rolipram, a drug that stops the loss of a growth-enhancing chemical called cyclic AMP, which occurs just after a spinal cord injury. Researchers then take cells from the rats’ peripheral nerves, grow those in the lab and transplant them into the injured area, followed by one-time injections of cyclic AMP above and below the transplant site. The injections raise the...