In 1988, physicians performed the first umbilical cord blood transplant on a 6-year-old boy with Fanconi anemia using a cord blood unit from an HLA-matched sibling. The success of this and subsequent cord blood transplants led to the establishment of cord blood banks that collect, process, tissue type and cryopreserve cord blood units (CBUs) for use in blood cell transplantation. Cord blood is being researched as an alternative cell source for hematopoietic reconstitution where an allogeneic transplant may be indicated. [http://www.marrow.org/DONOR/Donation_Transplant_Process/The_Donation_Procedure/CB_Donation/Advanced/index.html]
Cord Blood Donation Process
When a mother decides to donate her child's umbilical cord blood:
Doctors search the NMDP Registry of donors and cord blood units to find a match for their patients who need a transplant.
Umbilical Cord Blood Collection
Collecting cord blood poses no health risk to the mother or infant donor.
On average, about three to five fluid ounces are collected from the umbilical cord.
The collected cord blood is taken to a laboratory where it is tested and processed.
— It is tested for the HLA type, which is listed on the NMDP Registry and used to match the CBU with patients who need a transplant.
— Often, the red blood cells and plasma, which are not needed for transplants, are removed so the CBU takes less storage space.
— If the CBU meets eligibility standards, it is then stored in a plastic or vinyl bag in a liquid nitrogen freezer. It can be stored for a long time. Studies have shown good cell recovery after up to ten years of storage (Clin Exp Immunol 1997; 107, Suppl 1).
Process of Consent
The cord blood bank always gets the mother's written permission before banking the cord blood. The mother is also asked to provide a blood sample for infectious disease testing and to fill out health history forms.
Last Updated: March 2007
COLLECTS FOR: Research & Transplants
COLLECTS FROM: ANYWHERE!
PHONE: 1-877-LIFEBANKUSA (1-877-543-3226)
STORAGE: Cedar Knolls, NJ or Baton Rouge, LA
TRANSPLANT REGISTRIES: CRIR
LifebankUSA is one of only two banks that accepts donations mailed in from anywhere. LifebankUSA is a subsidiary of Celgene Cellular Therapeutics , a biotech pharmaceuticals company (Nasdaq: CELG). They primarily do business as a private cord blood bank. The LifebankUSA public donation program can be found under the "Medical Professionals" section of their website, but the best way to get information is to phone.
LIfebankUSA is the first cord blood bank to routinely bank the stem cells from the placenta, in addition to the umbilical cord blood. This is a separate process. They recommend collecting blood from the umbilical cord in utero, then the placenta is delivered and cells are extracted from the placenta.
LifebankUSA encourages parents to donate the placenta, re
gardless of how they are banking the umbilical cord blood.
COLLECTS FOR: Transplants
COLLECTS FROM: Selected hospitals in north Florida and south Alabama
PHONE: (352) 224-1600 or 334-1000
STORAGE: Shands Hospital at Univ of Florida, Gainesville, FL
TRANSPLANT REGISTRIES: BMDW, NMDP
This bank is a Participating Member of the National Marrow Donor Program (NMDP) cord blood bank network.
LifeCord is a program of LifeSouth Community Blood Centers, developed in cooperation with the University of Florida College of Medicine and the Shands at UF Stem Cell Laboratory. The medical director of LifeCord is John R. Wingard, M.D. As of Jan 2006, collections are accepted from:
North Florida Regional Medical Center,
Shands at AGH,
Shands at UF,
Shands at LakeShore,
The Birthing Center,
The Patient's Corner,
Baptist South and Baptist East Hospitals in Montgomery, Alabama
East Alabama Medical Center in Opelika, Alabama — starting Feb 2006